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Cardiac Surgery in Patients with Parkinson's Disease: A Retrospective Analysis of a High-Risk Cohort

Thomas Schroeter1, Maximilian Vondran1, Mahmoud Sleiman Wehbe1

  • 1Department of Cardiac Surgery, Heart Center Leipzig, Universitätsklinik, Leipzig, Germany.

The Thoracic and Cardiovascular Surgeon
|June 12, 2017
PubMed

Insights

Parkinson's disease (PD) patients undergoing cardiac surgery showed similar short- and long-term mortality rates compared to those without PD. This study indicates PD is not a significant risk factor for perioperative outcomes in cardiac surgery patients.

Area of Science:

  • Cardiology
  • Neurology
  • Surgical Outcomes

Background:

  • Limited understanding of perioperative course for Parkinson's disease (PD) patients undergoing cardiac surgery.
  • Need to identify PD's influence on perioperative outcomes and improve patient management.

Purpose of the Study:

  • To determine the impact of Parkinson's disease on the perioperative course of cardiac surgery patients.
  • To identify factors influencing outcomes and improve treatment strategies.

Main Methods:

  • Retrospective analysis of perioperative data from 130 cardiac surgery patients with PD.
  • 1:1 matched-pair analysis comparing PD patients with 130 controls without PD.
  • Analysis of 30-day and overall all-cause mortality, and associated risk factors.

Main Results:

  • No significant difference in 30-day (4.6% vs. 9.2%) or overall all-cause mortality (27.7% vs. 28.5%) between PD and control groups.
  • Emergency surgery and postoperative pneumonia were associated with 30-day mortality.
  • Independent predictors of mortality included age, NYHA class IV, and postoperative pneumonia.

Conclusions:

  • Parkinson's disease was not found to be a significant risk factor for perioperative morbidity or mortality in this cohort.
  • Outcomes for cardiac surgery patients with PD were similar to those without PD.
  • Further research may refine management strategies for PD patients undergoing cardiac procedures.
Abstract

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