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Effect of prostaglandin F2 alpha on brain and stomach 5-hydroxytryptamine

A K Sanyal, A Chakrabarti, R K Goel

The Journal of Pharmacy and Pharmacology

|April 1, 1985

Abstract:

PGF2 alpha initially inhibits the rate of 5-HT synthesis in both rat brain and stomach and subsequently stimulates it. The results suggest that PGs of E and F series modulate tryptaminergic neuronal activity which in its turn variously affects 5-HT mediated responses.

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