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Reflex Activity01:08

Reflex Activity

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A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort.
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
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Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

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Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
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Somatosensation01:33

Somatosensation

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The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
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Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

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Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
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Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

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Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
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Tactile and Chemical Senses01:27

Tactile and Chemical Senses

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Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
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Related Experiment Video

Updated: Feb 28, 2026

A Tactile Automated Passive-Finger Stimulator TAPS
19:44

A Tactile Automated Passive-Finger Stimulator TAPS

Published on: June 3, 2009

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Attention Robustly Gates a Closed-Loop Touch Reflex.

Dana Sherman1, Tess Oram2, David Harel3

  • 1Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.

Current Biology : CB
|June 13, 2017
PubMed
Summary
This summary is machine-generated.

Rats use attention to control whisker reflexes, specifically the touch-induced pump (TIP). Increased attention significantly boosts TIP occurrence for targeted object exploration, demonstrating precise sensory-motor regulation.

Keywords:
active touchattentionhierarchysensory-motor reflextop-down control

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Area of Science:

  • Neuroscience
  • Sensory-motor systems
  • Animal behavior

Background:

  • Rats utilize large whiskers (macrovibrissae) for environmental exploration via whisking motions.
  • Touch during whisking can trigger a rapid reflex called a touch-induced pump (TIP).
  • TIPs occur in approximately 25% of contacts in head-fixed rats.

Purpose of the Study:

  • To investigate the role of attention in regulating touch-induced pumps (TIPs) during whisker-object interactions.
  • To determine if attentional gating influences the timing and occurrence of TIPs.
  • To explore the neural mechanisms underlying attention-modulated whisker reflexes.

Main Methods:

  • Behavioral experiments with head-fixed rats exploring objects.
  • Quantification of TIP occurrence during tactile exploration.
  • Bilateral palpation experiments to assess unilateral attentional effects.
  • Development of a computational model to explain attentional gating mechanisms.

Main Results:

  • TIP occurrence increased from <30% to >65% when rats intentionally explored an object.
  • Attentional regulation of TIPs was unilateral and object-specific.
  • Computational modeling suggested attentional gating is not contact-triggered but rather a pre-existing or whisking-triggered scheme.
  • TIP latency remained unchanged despite increased occurrence with attention.

Conclusions:

  • Object-related attention significantly modulates whisker contact dynamics.
  • Attention regulates TIPs by gating a brainstem motor-sensory-motor loop.
  • This attentional regulation is optimized for rapid sensory processing and reaction.