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Other Pulmonary Disorders01:17

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Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
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Cough and bronchiectasis.

Paul McCallion1, Anthony De Soyza2

  • 1Physiotherapy Department and Adult Bronchiectasis Service Freeman Hospital, Newcastle Upon Tyne, UK.

Pulmonary Pharmacology & Therapeutics
|June 13, 2017
PubMed
Summary
This summary is machine-generated.

Bronchiectasis, a chronic lung disease causing airway dilation and infections, is rising. Chronic cough is a key symptom, impacting quality of life and treatment effectiveness, requiring multidisciplinary management.

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Area of Science:

  • Pulmonology
  • Respiratory Medicine
  • Clinical Science

Background:

  • Bronchiectasis is a chronic lung disease characterized by permanent airway dilatation, mucus retention, and recurrent infections.
  • Its prevalence is increasing, leading to significant morbidity and excess mortality.
  • Knowledge gaps persist regarding its epidemiology, pathophysiology, prognosis, and optimal treatments.

Purpose of the Study:

  • To review current concepts in bronchiectasis.
  • To focus on the complex aspects of chronic cough in bronchiectasis patients.
  • To highlight unknowns in managing chronic cough associated with this condition.

Main Methods:

  • Literature review of current concepts in bronchiectasis.
  • Focus on the role and management of chronic cough.
  • Discussion of contributing factors and complexities of cough syndromes.

Main Results:

  • Chronic cough is a common presenting symptom in bronchiectasis, affecting quality of life.
  • Cough hypersensitivity and airway hyperresponsiveness can impede treatment efficacy.
  • Post-nasal drip and gastro-oesophageal reflux may exacerbate intractable cough.

Conclusions:

  • Effective airway clearance and physiotherapy are crucial for bronchial toileting.
  • Cough sensitization syndromes and multiple interacting cough causes necessitate careful assessment.
  • Multidisciplinary approaches are essential for optimizing symptom control in bronchiectasis-related chronic cough.