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Related Concept Videos

Oogenesis02:07

Oogenesis

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Related Experiment Video

Updated: Feb 28, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
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Spontaneous intergluteal cleft endometriosis.

E Furet1, S Bendifallah1, M Ballester1

  • 1Clinical Research Group: GRC-6 UPMC, Centre Expert En Endométriose (C3E), UMRS-938, service de gynécologie obstétrique, hôpital Tenon, AP-HP, université Pierre-et-Marie-Curie Paris 6, Paris, France.

Journal of Gynecology Obstetrics and Human Reproduction
|June 13, 2017
PubMed
Summary
This summary is machine-generated.

This study details the first reported case of intergluteal cleft endometriosis, a rare form of skin endometriosis. The condition presented with cyclical pain and bleeding linked to menstruation.

Keywords:
EndometriosisIntergluteal cleftSubcutaneaous endometriosis

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Area of Science:

  • Gynecology
  • Dermatology
  • Pathology

Background:

  • Endometriosis involves endometrial tissue outside the uterus, typically in the pelvic region.
  • Extra-abdominal endometriosis is uncommon, with cutaneous involvement being particularly rare.
  • Subcutaneous endometriosis presents a diagnostic challenge due to its infrequent occurrence.

Observation:

  • A patient presented with cyclical pain and bleeding in the intergluteal cleft.
  • Symptoms correlated with the menstrual cycle, suggesting a hormonal influence.
  • Physical examination revealed localized tissue in the intergluteal region.

Findings:

  • The case represents the first documented instance of spontaneous intergluteal cleft endometriosis.
  • Histopathological analysis confirmed the presence of endometrial tissue in the subcutaneous layer.
  • This finding expands the known spectrum of endometriosis presentation.

Implications:

  • Highlights the importance of considering endometriosis in the differential diagnosis of cyclical symptoms in unusual skin locations.
  • Suggests that endometriosis can manifest in the intergluteal region, requiring specific diagnostic and management approaches.
  • Underscores the need for increased awareness among clinicians regarding rare extra-abdominal endometriosis presentations.