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Sickle cell hemoglobinopathies: a protocol for management.

R W Kinsey, J B Ballard, V J Matukas

    Journal of Oral Surgery (American Dental Association : 1965)
    |June 1, 1979
    PubMed
    Summary
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    Orthognathic surgery can reveal latent sickle cell disease. A screening protocol for patients with abnormal hemoglobin, including transfusions and careful monitoring, is crucial for safe surgical outcomes.

    Area of Science:

    • Oral and Maxillofacial Surgery
    • Hematology
    • Anesthesiology

    Background:

    • Orthognathic surgery is elective surgery to correct jaw irregularities.
    • Patients with abnormal hemoglobin, such as sickle cell disease, require special management.
    • Undiagnosed hemoglobinopathies can lead to surgical complications.

    Observation:

    • A case presented with sickle cell disease complications post-orthognathic surgery.
    • A protocol was developed to manage patients with abnormal hemoglobins undergoing orthognathic surgery.
    • The protocol involves screening, hemoglobin electrophoresis, and transfusion management.

    Findings:

    • Screening identifies patients with abnormal hemoglobin.
    • Transfusions aim to maintain abnormal hemoglobin levels below 40%.

    Related Experiment Videos

  • Perioperative care focuses on oxygenation and normothermia.
  • Postoperative monitoring includes serial electrophoreses and transfusions as needed.

    • Implications:

    • This protocol can prevent sickle cell disease-related complications during orthognathic surgery.
    • It provides a framework for managing patients with hemoglobinopathies.
    • Early identification and intervention are key to patient safety.