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Related Concept Videos

Brain Waves01:23

Brain Waves

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Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:
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Related Experiment Video

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Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
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Electroencephalography Patterns and Prognosis in Acute Ischemic Stroke.

Fabricio O Lima1,2, João A G Ricardo3,4, Ana C Coan5,2

  • 1Health Sciences Center, University of Fortaleza, Fortaleza, Brazil.

Cerebrovascular Diseases (Basel, Switzerland)
|June 13, 2017
PubMed
Summary

Interictal epileptiform discharges (IED) and periodic patterns (PP) on EEG in acute ischemic stroke indicate a worse functional outcome. Early detection of epileptiform activity (EA) is crucial for stroke prognosis.

Keywords:
ElectroencephalographyOutcomePeriodic patternsSeizuresStroke

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Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

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Area of Science:

  • Neurology
  • Neurophysiology
  • Stroke Medicine

Background:

  • The prognostic value of interictal epileptiform discharges (IED) and periodic patterns (PP) following ischemic stroke remains unclear.
  • Electroencephalography (EEG) is a key tool for assessing brain activity post-stroke.

Purpose of the Study:

  • To determine if IED and PP, detected via EEG during acute ischemic stroke, correlate with poorer functional outcomes.
  • To investigate the prognostic significance of epileptiform activity (EA) in stroke patients.

Main Methods:

  • Prospective enrollment of 157 adult patients with acute ischemic stroke within 72 hours of onset.
  • Exclusion of patients with pre-stroke seizures, epilepsy, or conditions precluding EEG.
  • EEG interpretation by a blinded neurophysiologist, defining IED and PP (grouped as EA) per guidelines. Outcome assessed using modified Rankin Scale at 3 months.

Main Results:

  • Univariable analysis showed admission NIHSS, age, and presence of EA were associated with 3-month outcome.
  • Multivariable analysis revealed that only admission NIHSS and the presence of EA were independent predictors of prognosis.
  • The presence of EA (OR 2.27, 95% CI 1.04-5.00, p=0.04) significantly predicted a worse outcome.

Conclusions:

  • The presence of epileptiform activity (EA) on EEG during the acute phase of ischemic stroke is an independent predictor of worse functional outcome.
  • Further research is needed to explore EEG's role in stroke prognosis, including medication effects and seizure occurrence in patients with specific EEG patterns.