[Changes in electrocardiographic parameters in children with complete left bundle branch block early after

Li Wei1, Yong-Yi Lu, Yi-Min Hua

  • 1Department of Pediatrics, West China Second University Hospital/Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu 610041, China. yeqianghua949@sohu.com.

Insights

Electrocardiographic parameters like left ventricular voltage and JTcd differ significantly in children with complete left bundle branch block (CLBBB) after ventricular septal defect (VSD) closure. JTcd may help predict CLBBB development post-VSD intervention.

Area of Science:

  • Pediatric Cardiology
  • Electrophysiology
  • Interventional Cardiology

Background:

  • Complete left bundle branch block (CLBBB) can occur after transcatheter closure of ventricular septal defects (VSDs).
  • Electrocardiographic (ECG) changes following VSD closure require further investigation, particularly in children with pre-existing CLBBB.

Purpose of the Study:

  • To evaluate changes in ECG parameters in pediatric patients with CLBBB after transcatheter VSD closure.
  • To compare ECG indices between children with and without CLBBB post-VSD intervention.

Main Methods:

  • A cohort of 21 children with CLBBB and 21 matched controls without arrhythmias were studied after perimembranous VSD transcatheter closure.
  • ECG parameters including left ventricular voltage, QT interval, and JT dispersion (JTcd) were measured before and at multiple time points after the procedure.

Main Results:

  • Left ventricular voltage and JTcd showed significant changes over time in both groups.
  • Significant differences in JTcd and left ventricular voltage were observed between the CLBBB and control groups post-procedure.

Conclusions:

  • Significant ECG differences, specifically in left ventricular voltage and JTcd, exist between pediatric VSD patients with and without CLBBB early after transcatheter closure.
  • JTcd may serve as a potential predictor for the early development of CLBBB following transcatheter VSD closure.
Abstract

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