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Ultrasound-guided drug delivery in cancer

Sayan Mullick Chowdhury1, Taehwa Lee1, Jürgen K Willmann1

  • 1Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.

Ultrasonography (Seoul, Korea)
|June 14, 2017
PubMed

Keywords:
Cancer therapyDrug delivery systemsGenetic therapyMicrobubblesUltrasonography

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Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
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