Improved working ability in a contemporary MS population compared with a historic non-treated MS population in the

Anne Wickström1, Peter Sundström1, Lucas Wickström2

  • 1Department of Pharmacology and Clinical Neuroscience, Umeå University, Sweden.

Abstract

Insights

Disease-modifying drugs (DMDs) and work support significantly improved work ability in multiple sclerosis (MS) patients. Labor market participation rose, while disability pensions decreased, showing better work outcomes for MS individuals.

Area of Science:

  • Neurology
  • Occupational Health
  • Public Health

Background:

  • Multiple sclerosis (MS) frequently impairs individuals' capacity to work.
  • Optimizing disease management and adapting work environments can enhance work ability in MS patients.

Purpose of the Study:

  • To compare sickness absence rates between MS patients who received disease-modifying drug (DMD) treatments and/or active work-promoting measures versus those who did not.
  • To evaluate the impact of modern treatment and support strategies on the working lives of individuals with MS.

Main Methods:

  • A comparative study of MS patients in Västerbotten County, Sweden, in 2013, a period with widespread DMD use.
  • Comparison with a historical cohort from the same region before DMD availability and work-promoting measures.
  • Analysis of sickness absence data, labor market participation, and disability pension rates.

Main Results:

  • The proportion of MS patients in the labor market or studying increased significantly from 38% to 70% (p < 0.001).
  • The rate of full-time disability pensions decreased from 27% to 12% (p < 0.001).
  • Sickness absence showed a significant reduction across various Expanded Disability Status Scale (EDSS) grades.

Conclusions:

  • Treatment with DMDs, alongside active work-promoting initiatives, demonstrably improves work ability in individuals with MS.
  • These combined interventions contribute to better vocational outcomes and reduced reliance on disability pensions for MS patients.

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