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Updated: Jul 20, 2026
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control
M W Gustavsen1, E G Celius1, B S Winsvold1
1Department of Neurology, Oslo University Hospital, Norway.
Background:
Inconsistent results have been obtained with regard to headache comorbidity in multiple sclerosis (MS).
Objective:
Investigate the one-year prevalence of migraine and tension-type headache (TTH) in Norwegian MS patients and relate this to clinical parameters.
Methods:
A questionnaire concerning headache was administered to 756 MS patients and 1090 controls and used to determine the one-year prevalence of migraine and frequent TTH.
Results:
No significant differences were seen between patients and controls or between patients with different disease course. Less migraine was observed in patients with Expanded Disability Status Scale score (EDSS) ≥4.0.
Conclusions:
This case-control study does not support an association between migraine or TTH and MS.
