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Updated: Feb 28, 2026

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
Platelet-rich plasma (PRP) for knee disorders.
1St Michael's Hospital, 30 Bond Street, Toronto, M5B1W8, Canada.
Platelet-rich plasma (PRP) therapy utilizes concentrated platelets from a patient's own blood to promote healing. This review examines recent evidence and UK guidelines on PRP's effectiveness for knee injuries and osteoarthritis.
Area of Science:
- Orthopedics
- Regenerative Medicine
- Biotechnology
Background:
- Platelet-rich plasma (PRP) is an autologous blood concentrate with elevated platelet levels.
- Platelets release growth factors that stimulate tissue regeneration.
- PRP is increasingly used for knee conditions, including cartilage damage, ligament, and meniscal injuries.
Purpose of the Study:
- To review the latest evidence on the use of PRP in the knee.
- To examine current UK National Institute of Health & Clinical Excellence (NICE) guidelines regarding PRP for osteoarthritis.
Main Methods:
- Literature review of recent studies on PRP for knee pathologies.
- Analysis of current NICE guidelines concerning osteoarthritis and PRP interventions.
Main Results:
- Growing evidence supports PRP use in specific knee indications.
- The review synthesizes recent findings and clinical guidelines.
Conclusions:
- PRP demonstrates potential therapeutic benefits for various knee conditions.
- Clinical application of PRP in knee injuries and osteoarthritis requires consideration of current evidence and guidelines.
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