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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Cytotoxic T Cells-mediated Immune Response01:27

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
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Cell-mediated Immune Responses01:40

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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Related Experiment Video

Updated: Feb 28, 2026

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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Cellular immunity augmentation in mainstream oncologic therapy.

Daohong Chen1, Xiaoshi Zhang1

  • 1Research Institute of Biomedicine, Yiling Pharmacy, Shijiazhuang 050035, China.

Cancer Biology & Medicine
|June 14, 2017
PubMed
Summary

Anticancer immunotherapy, particularly cellular immunity augmentation, has become a major cancer treatment. This review updates on established treatments that boost cell immunity for combating malignancies.

Keywords:
Cellular immunityoncologypharmaceutical innovation

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Area of Science:

  • Oncology and Immunology

Background:

  • Anticancer immunotherapy has evolved significantly, becoming a mainstream oncology treatment in the last five years.
  • Cellular immunity is crucial for anti-tumor responses but is often suppressed during cancer progression.

Purpose of the Study:

  • To provide a comprehensive update on clinically established anticancer treatments.
  • To focus on therapies that augment cellular immunity as their primary mechanism of action.

Main Methods:

  • Review of clinically established anticancer treatments.
  • Focus on treatments utilizing cell immunity augmentation.

Main Results:

  • Cellular immunity-based therapies have shown high efficacy in specific cancer patient populations.
  • These advancements have transformed oncologic medicine and pharmaceutical innovation.

Conclusions:

  • Cellular immunity augmentation represents a significant milestone in cancer treatment.
  • Contemporary breakthroughs in immunology and genetic engineering enable re-activation of cellular immunity against cancer.