Related Experiment Video
Updated: Feb 28, 2026

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
Perforator Flaps Covering Alloplastic Materials in Full-Thickness Chest Wall Defects Reconstruction: A Safe Option?
Cristina Aubá1, Álvaro Cabello1, Emilio García-Tutor1
1Department of Plastic and Reconstructive Surgery, Clínica Universidad de Navarra, Spain; Department of Plastic and Reconstructive Surgery Hospital Universitario Guadalajara, Guadalajara, Spain; and Department of Thoracic Surgery, Clinica Universidad de Navarra, Spain.
Perforator flaps combined with alloplastic materials offer a reliable solution for large chest wall defects. This approach ensures stability and adequate soft-tissue coverage, addressing previous concerns about vascularization.
Area of Science:
- Plastic Surgery
- Thoracic Surgery
- Reconstructive Surgery
Background:
- Large full-thickness chest wall defects necessitate alloplastic materials for stability and flaps for soft-tissue coverage.
- Perforator flaps are often avoided due to concerns about inadequate vascularization over inert materials.
Observation:
- This study evaluated the use of perforator flaps with alloplastic materials in four patients with full-thickness chest wall defects.
- Reconstructions utilized double Marlex mesh or Goretex patches combined with deep inferior epigastric artery perforator or lumbar artery perforator flaps.
Findings:
- The combination of perforator flaps and alloplastic materials (Marlex mesh, acrylic cement, or Goretex) yielded encouraging results in chest wall reconstruction.
- This technique provided both chest wall stability and adequate soft-tissue coverage.
Implications:
- Perforator flaps in conjunction with alloplastic materials represent a viable and reliable option for complex full-thickness chest wall defect reconstruction.
- This approach may overcome limitations associated with traditional methods and minimize donor-site morbidity.

