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Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial

Detian Yuan1, Shan Huang2, Emanuel Berger3

  • 1Institute of Virology, Technische Universität München and Helmholtz Zentrum München, 81675 Munich, Germany; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

Cancer Cell
|June 14, 2017
PubMed

Keywords:
JNKKupffer cellTnfcholastasisintrahepatic cholangiocarcinomamitochondrial dysfunctionpro-inflammatory nichereactive oxygen speciesunfolded protein response

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