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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Intestinal tuberculosis: a diagnostic challenge.

J Kentley1, J L Ooi2,3, J Potter1,4

  • 1Department of Respiratory Medicine, Barts Health NHS Trust, London, UK.

Tropical Medicine & International Health : TM & IH
|June 14, 2017
PubMed
Summary
This summary is machine-generated.

Delayed diagnosis of intestinal tuberculosis (ITB) is common, especially in low-burden countries. Prompt diagnosis in patients from TB-endemic areas is crucial to prevent morbidity.

Keywords:
TBLondonLondresabdominalgastro-intestinalgastrointestinaltuberculosis

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System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Public Health

Background:

  • Intestinal tuberculosis (ITB) is a significant concern, particularly in individuals migrating from tuberculosis-endemic regions.
  • Accurate and timely diagnosis of ITB can be challenging, leading to potential delays and increased patient morbidity.

Purpose of the Study:

  • To characterize the clinical presentation, diagnostic timelines, and key findings in patients diagnosed with intestinal tuberculosis (ITB).
  • To highlight the diagnostic challenges and potential pitfalls in identifying ITB in a low-prevalence setting.

Main Methods:

  • A retrospective analysis of 61 consecutive patients diagnosed with ITB between 2008 and 2014.
  • Data collection focused on patient demographics, symptom onset, time to diagnosis, diagnostic modalities, and ITB involvement sites.

Main Results:

  • The study population predominantly comprised males (66%) with a mean age of 34.6 years, and 93% were foreign-born from TB-endemic areas.
  • Median time from symptom onset to ITB diagnosis was 13 weeks, with 16% initially misdiagnosed as Inflammatory Bowel Disease (IBD).
  • Commonly affected sites included the ileocaecum (44%) and small bowel (34%); diagnosis was confirmed histologically/microbiologically in 69% of cases.

Conclusions:

  • Delayed diagnosis of ITB contributes to significant patient morbidity.
  • ITB should be considered in patients presenting with abdominal complaints, especially those from TB-endemic regions.
  • Diagnostic tools such as axial imaging, colonoscopy, and tissue biopsy are essential for confirming ITB.