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Updated: Feb 28, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Sclerosing mesenteritis and mesenteric panniculitis - clinical experience and radiological features
Lisa Nyberg1, Jan Björk2, Peter Björkdahl3
1Department of Medicine, Division of Gastroenterology, Hospital of Trelleborg, Trelleborg, Sweden. adolfssonlisa@hotmail.com.
Sclerosing mesenteritis (SM) and mesenteric panniculitis (MP) are distinct conditions. MP shows stable radiology with mild symptoms, while SM presents with atypical radiology and a more aggressive clinical course.
Area of Science:
- Gastroenterology
- Radiology
- Pathology
Background:
- Sclerosing mesenteritis (SM) is an umbrella term for idiopathic mesenteric inflammatory conditions.
- Mesenteric panniculitis (MP) is a radiological finding with an unclear relationship to clinical SM.
- The study aimed to correlate radiological findings with the clinical disease course of SM and MP.
Purpose of the Study:
- To differentiate between mesenteric panniculitis (MP) and sclerosing mesenteritis (SM).
- To investigate the relationship between radiological findings and clinical presentation in these conditions.
- To propose a refined classification for these mesenteric inflammatory diseases.
Main Methods:
- Retrospective descriptive study of patients with idiopathic mesenteric inflammation.
- Inclusion criteria: histological verification of SM or radiological evidence of MP.
- Analysis of radiological findings, clinical symptoms, and disease course.
Main Results:
- Two patient subgroups were identified based on radiological and clinical features.
- Mesenteric panniculitis (MP) group (23/27 patients) exhibited typical radiology and mild-to-moderate symptoms.
- Sclerosing mesenteritis (SM) group (4 patients) showed atypical radiology, systemic inflammation, and a more severe clinical course, responding to corticosteroids.
Conclusions:
- Mesenteric panniculitis (MP) is characterized by stable, typical radiological changes and a milder course.
- Sclerosing mesenteritis (SM) is associated with atypical radiology, aggressive clinical behavior, and systemic inflammation.
- The term sclerosing mesenteritis (SM) should be reserved for the aggressive subgroup with atypical radiological findings.
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