Related Experiment Video
Updated: Feb 28, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
Air density dependence of the response of the PTW SourceCheck 4pi ionization chamber for 125I brachytherapy seeds
J Torres Del Río1, A M Tornero-López2, D Guirado1
1Unidad de Radiofísica, Hospital Clínico Universitario San Cecilio, E-18016 Granada, Spain.
Purpose:
To analyze the air density dependence of the response of the new SourceCheck 4pi ionization chamber, manufactured by PTW.
Methods:
The air density dependence of three different SourceCheck 4pi chambers was studied by measuring 125I sources. Measurements were taken by varying the pressure from 746.6 to 986.6hPa in a pressure chamber. Three different HDR 1000 Plus ionization chambers were also analyzed under similar conditions. A linear and a potential-like function of the air density were fitted to experimental data and their achievement in describing them was analyzed.
Results:
SourceCheck 4pi chamber response showed a residual dependence on the air density once the standard pressure and temperature factor was applied. The chamber response was overestimated when the air density was below that under normal atmospheric conditions. A similar dependence was found for the HDR 1000 Plus chambers analyzed. A linear function of the air density permitted a very good description of this residual dependence, better than with a potential function. No significant variability between the different specimens of the same chamber model studied was found.
Conclusion:
The effect of overestimation observed in the chamber responses once they are corrected for the standard pressure and temperature may represent a non-negligible ∼4% overestimation in high altitude cities as ours (700m AMSL). This overestimation behaves linearly with the air density in all cases analyzed.
Related Concept Videos
Biological Effects of Radiation
Inductively Coupled Plasma Atomic Emission Spectroscopy: Principle
The ions and electrons produced interact with the fluctuating magnetic field created by a water-cooled...
Atomic Emission Spectroscopy: Lab
Atomic Absorption Spectroscopy: Radiation and Light Sources
Two common narrow-range 'line' sources used in AAS are hollow-cathode lamps (HCLs) and...
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences

