Psychoneuroimmunoendocrinology: clinical implications
Sandra Nora González-Díaz1, Alfredo Arias-Cruz1, Bárbara Elizondo-Villarreal1
1Department of Allergy and Clinical Immunology Service, University Hospital "Dr. José Eleuterio González" Autonomous University of Nuevo Leon (UANL), Monterrey, Nuevo León 64460 Mexico.
The World Allergy Organization Journal
|June 16, 2017
Summary
Psychoneuroimmunoendocrinology explores the mind-body-immune connection. Stress and epigenetic factors impact this axis, contributing to various diseases, highlighting its importance in pathology.
Area of Science:
- Psychoneuroimmunoendocrinology
- Integrative medicine
- Mind-body science
Background:
- Psychoneuroimmunoendocrinology, established in 1936, studies the intricate interplay between psychological, neural, endocrine, and immune systems.
- This field seeks to apply this knowledge to treat a wide range of conditions, including allergic, autoimmune, and cardiovascular diseases.
Purpose of the Study:
- To deepen the understanding of psychoneuroimmunoendocrinology.
- To elucidate the critical role of the psychoneuroimmunoendocrine axis in the development of numerous pathologies.
Main Methods:
- A comprehensive literature review was conducted.
- Searches included descriptive studies, experimental research, and reviews published in PubMed from 1936 to 2016.
Main Results:
- The psychoneuroimmunoendocrine axis is significantly influenced by epigenetic factors and stress.
- These influences operate through distinct pathways and neurotransmitters, leading to disease emergence.
Conclusions:
- The interactions within the psychoneuroimmunoendocrine system are fundamental to the etiology of diverse diseases.
- Further understanding of this axis is crucial for advancing medical treatments.
Keywords:
AllergyBehaviorEndocrine systemImmune systemImmunologyNervous systemPsychiatryPsychological disordersPsychoneuroimmunoendocrinologyStressMore Related Videos
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