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Redefining disease emergence to improve prioritization and macro-ecological analyses
Samantha R Rosenthal1, Richard S Ostfeld2, Stephen T McGarvey1,3
1Department of Epidemiology, School of Public Health, Brown University, 121 S Main Street Box G-S121-2, Providence, RI 02912, United States.
The definition of emerging infectious diseases (EIDs) needs refinement to better prioritize global health threats. A new framework distinguishes EIDs from emerging and novel pathogens for improved surveillance and resource allocation.
Area of Science:
- Microbiology
- Epidemiology
- Public Health
Background:
- Interest in emerging infectious diseases (EIDs) is rapidly increasing.
- The term 'emerging infectious disease' has evolved, causing confusion in literature and research.
- Current definitions may impede effective prioritization of global health threats.
Purpose of the Study:
- To review the evolution of the term 'emerging infectious disease' (EID) in human health literature.
- To propose a new framework for classifying and prioritizing disease and pathogen emergence.
- To illustrate how EID definitions impact conclusions on emergence pathways and drivers.
Main Methods:
- Literature review of the term 'emerging infectious disease' (EID).
- Analysis of disease emergence pathways (speciation, strain differentiation, geographic expansion).
- Development and proposal of a new framework for pathogen and disease classification.
Main Results:
- The evolution of the EID term has led to inconsistencies.
- Existing definitions may hinder effective prioritization of EIDs and pathogens.
- A new framework is proposed to distinguish EIDs, emerging pathogens, and novel potential pathogens.
Conclusions:
- A refined classification system is crucial for prioritizing global health threats.
- The proposed framework distinguishes between EIDs, emerging pathogens, and novel potential pathogens.
- Prioritization strategies include adaptation for EIDs, prevention for emerging pathogens, and surveillance for novel pathogens.
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