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Liver segmentation: indications, techniques and future directions.

Akshat Gotra1,2, Lojan Sivakumaran3,4, Gabriel Chartrand5

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Liver segmentation using CT and MRI is crucial for assessing liver volume before major surgeries. Automated methods offer efficiency, expanding clinical applications in surgical planning and biomarker integration.

Keywords:
AutomatedComputed tomographyLiverMagnetic resonance imagingSegmentationVolumetry

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Area of Science:

  • Medical Imaging and Radiology
  • Computational Anatomy
  • Surgical Planning

Background:

  • Liver volumetry is increasingly vital in clinical practice.
  • Accurate liver volume assessment relies on organ segmentation from CT and MRI scans.
  • Radiologists and healthcare professionals require accessible knowledge on liver segmentation techniques.

Purpose of the Study:

  • To provide a comprehensive overview of liver segmentation methods.
  • To detail the clinical indications and evolving roles of liver segmentation.
  • To guide healthcare professionals in utilizing segmentation for liver volumetry.

Main Methods:

  • Review of indications for liver segmentation in clinical practice.
  • Analysis of technical approaches in segmentation software (manual, semi-automated, automated).
  • Examination of current and emerging applications of liver segmentation.

Main Results:

  • Liver segmentation is indicated for procedures like hepatectomy, portal vein embolization, ALPPS, and transplantation.
  • Segmentation software varies in user input: manual (gold standard, time-consuming), semi-automated, and fully automated (efficient but potential pitfalls).
  • Emerging applications include enhanced surgical planning and integration with MRI-based biomarkers.

Conclusions:

  • Liver segmentation offers diverse and expanding clinical applications.
  • Semi-automated and fully automated segmentation tools enable efficient clinical integration of volumetry.
  • Continued development in automated segmentation promises greater robustness and wider adoption.