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Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation
Published on: November 10, 2023
Laryngotracheal Involvement in Systemic Light Chain Amyloidosis
Daniel T Ginat1, Jefree Schulte2, Louis Portugal3
1Department of Radiology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL, 60637, USA. dtg1@uchicago.edu.
Abstract:
Laryngotracheal amyloid deposition is an uncommon manifestation of systemic light chain amyloidosis. Diagnostic imaging, such as CT, is useful for suggesting the possibility of amyloidosis and delineating the extent of the lesions for surgical management; however, the diagnosis is confirmed with the histologic finding of amorphous eosinophilic material which stains positively for Congo red and may show apple green birefringence on polarization. These features are exemplified in this sine qua non radiology-pathology correlation article.
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