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Priorities for methodological research on patient and public involvement in clinical trials: A modified Delphi

Anna Kearney1, Paula Williamson1, Bridget Young2

  • 1Clinical Trials Research Centre (CTRC), North West Hub for Trials Methodology, University of Liverpool, Liverpool, UK.

Health Expectations : an International Journal of Public Participation in Health Care and Health Policy
|June 16, 2017
PubMed
Abstract

Insights

This study identified top UK research priorities for patient and public involvement (PPI) in clinical trials. Key areas include building researcher-PPI relationships, selecting patient-important outcomes, and improving trial information accessibility.

Area of Science:

  • Clinical Trials Methodology
  • Health Services Research
  • Patient and Public Involvement (PPI)

Background:

  • There is a growing international interest in patient and public involvement (PPI) in clinical trials.
  • However, evidence on efficient, effective, and acceptable methods for implementing PPI in clinical trials is lacking.

Purpose of the Study:

  • To identify the methodological research priorities of UK PPI stakeholders.
  • To address uncertainties surrounding the implementation of PPI in clinical trials.

Main Methods:

  • A modified Delphi process was employed.
  • This involved a two-round online survey and a stakeholder consensus meeting.
  • A total of 219 participants completed the surveys, and 25 attended the consensus meeting.

Main Results:

  • The top three prioritized research topics were identified.
  • These include developing strong working relationships between researchers and PPI contributors.
  • Other priorities involve exploring PPI in selecting trial outcomes and improving the accessibility of trial information for participants.

Conclusions:

  • The prioritized topics highlight critical areas of uncertainty in PPI for clinical trials.
  • Addressing these research gaps is essential for enhancing PPI effectiveness.
  • Findings can guide the planning and funding of PPI research to minimize waste and focus efforts.
Keywords:
Delphiclinical trialspatient and public involvementresearch priorities

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