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Published on: September 26, 2018
Hypertension: Overly important but under-controlled
Monique Eam van Kleef1, Wilko Spiering1
1Department of Vascular Medicine, University Medical Center Utrecht, The Netherlands.
Insights
High blood pressure (hypertension) remains a major cause of cardiovascular disease. This review addresses key challenges in hypertension diagnosis and treatment for secondary cardiovascular prevention.
Area of Science:
- Cardiology
- Public Health
- Internal Medicine
Background:
- Hypertension is the primary global cause of cardiovascular disease and mortality.
- Despite awareness, hypertension prevalence is rising worldwide, indicating a need for improved management strategies.
- Significant gaps exist in hypertension awareness, treatment, and control, particularly in secondary cardiovascular prevention.
Purpose of the Study:
- To review five critical issues in managing hypertension for secondary cardiovascular disease prevention.
- To identify knowledge gaps, implementation barriers, and potential solutions for optimizing hypertension care.
Main Methods:
- This review synthesizes current knowledge on hypertension diagnosis and treatment.
- Key areas examined include out-of-office blood pressure monitoring, secondary hypertension detection, lifestyle modifications, medication adherence, and blood pressure targets.
- The review analyzes existing evidence, identifies knowledge deficits, and discusses barriers to guideline implementation.
Main Results:
- Challenges in hypertension diagnosis include accurate out-of-office measurements and effective secondary hypertension detection.
- Key treatment issues involve optimizing lifestyle changes, improving medication adherence, and defining appropriate blood pressure targets.
- Barriers to optimal management hinder the full implementation of current hypertension guidelines.
Conclusions:
- Improving hypertension diagnosis and treatment is crucial for secondary cardiovascular prevention.
- Addressing knowledge gaps and implementation barriers can enhance patient outcomes and reduce cardiovascular disease burden.
- A multi-faceted approach is needed to tackle the escalating global hypertension crisis.
Abstract:
Hypertension is the leading cause of cardiovascular disease and death. Despite increased knowledge of its importance in cardiovascular disease, the worldwide prevalence is still increasing and there is considerable scope for improvement of awareness, treatment and control. In this review, five major issues in hypertension management in secondary prevention of cardiovascular disease will be outlined. The first two issues will address hypertension diagnosis: out-of-office blood pressure measurements and the detection of secondary hypertension. The last three issues will address hypertension treatment: lifestyle modification, medication adherence and blood pressure targets. For each of the five issues, we will outline existing knowledge, gaps in existing knowledge, barriers preventing full implementation of guideline recommendations, and possible solutions to improve management of the current disquieting situation.
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Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...

