Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cross-reactivity00:42

Cross-reactivity

33.1K
Overview
33.1K
Reactivity of Enols01:18

Reactivity of Enols

4.1K
Enols are a class of compounds where a hydroxyl group is attached to a carbon–carbon double bond, which implies that it is a vinyl alcohol. A carbonyl compound with an α hydrogen undergoes keto–enol tautomerism and remains in equilibrium with its tautomer, the enol form. Usually, the keto tautomer is present in a higher concentration than the enol tautomer due to the higher bond energy of C=O compared to C=C. Moreover, the direction of the keto–enol equilibrium is...
4.1K
Fixed Action Patterns01:06

Fixed Action Patterns

17.7K
A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
17.7K
Reactivity of Enolate Ions01:23

Reactivity of Enolate Ions

3.4K
Enolate ions are formed by the acid–base reaction of a carbonyl compound with a base. This leads to deprotonation of the α hydrogen atom, leading to a resonance-stabilized enolate ion where one of the contributing structures is an oxyanion, which imparts additional stability. Therefore, the proton on the α carbon is more acidic in nature than that of other sp3-hybridized C–H bonds but less acidic than those in O–H bonds where the negative charge in the conjugate...
3.4K
Patterns of Fever01:26

Patterns of Fever

3.9K
Before understanding the types and patterns of fever, it is essential to know its phases.
3.9K
Radical Reactivity: Overview01:11

Radical Reactivity: Overview

2.8K
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coordinated immune-epithelial dynamics in the nasal epithelium protect against respiratory virus infection.

bioRxiv : the preprint server for biology·2026
Same author

Reactive and therapy induced bone marrow changes linked to systemic infectious and non-infectious disorders including MAS/HLH report from the European association for haematopathology, Dubrovnik 2024.

Virchows Archiv : an international journal of pathology·2026
Same author

Application of Hi-C sequencing to detect oncogene rearrangements for diagnosis and treatment of large B-cell lymphoma.

Blood advances·2026
Same author

Mast Cells in Acute COVID-19 Patients.

Allergy·2026
Same author

The genetic landscape of extramedullary plasmacytoma: a comparative analysis with extramedullary disease of multiple myeloma.

Haematologica·2026
Same author

Myeloid/lymphoid precursor cell neoplasms and mixed phenotype acute leukemias: A Bone Marrow Workshop Report from the 22nd European Association for Hematopathology/Society of Hematopathology Meeting, Dubrovnik, 2024.

American journal of clinical pathology·2026

Related Experiment Video

Updated: Feb 5, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

5.4K

A pattern-based approach to reactive lymphadenopathies.

Alexandar Tzankov1, Stephan Dirnhofer1

  • 1Institute of Pathology, University Hospital Basel, Basel, Switzerland.

Seminars in Diagnostic Pathology
|June 17, 2017
PubMed
Summary

Differentiating benign reactive lymphadenopathy from malignant lymphoma is critical in histopathology. This review outlines a pattern-based approach to reactive lymphadenopathies, improving diagnostic accuracy and guiding ancillary testing.

Keywords:
HistopathologyLymphadenopathyPatternsReactive lymph node changes

More Related Videos

Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV
10:42

Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV

Published on: December 29, 2016

11.2K
Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis
08:46

Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis

Published on: September 16, 2014

8.2K

Related Experiment Videos

Last Updated: Feb 5, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

5.4K
Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV
10:42

Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV

Published on: December 29, 2016

11.2K
Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis
08:46

Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis

Published on: September 16, 2014

8.2K

Area of Science:

  • Histopathology
  • Oncology
  • Immunology

Background:

  • Distinguishing benign from malignant enlarged lymph nodes is a critical diagnostic challenge.
  • Misdiagnosis of benign lymphadenopathies as lymphomas is a common error in cancer diagnostics.
  • Accurate histopathological diagnosis is essential for effective patient management and treatment.

Purpose of the Study:

  • To provide a synopsis of a histopathological pattern-based approach for diagnosing reactive lymphadenopathies.
  • To emphasize the importance of recognizing distinct histopathological patterns in lymph node examination.
  • To enhance the efficiency and targetability of ancillary diagnostic techniques.

Main Methods:

  • Review of established histopathological patterns associated with reactive lymphadenopathies.
  • Correlation of specific patterns with potential causative agents.
  • Emphasis on differential diagnosis based on morphological features.

Main Results:

  • Identification of distinct histopathological patterns characteristic of reactive lymph node changes.
  • Demonstration of how pattern recognition aids in narrowing down differential diagnoses.
  • Highlighting the link between precise histopathological diagnosis and efficient use of ancillary tests.

Conclusions:

  • A pattern-based approach to reactive lymphadenopathies improves diagnostic accuracy in histopathology.
  • Accurate differentiation of benign from malignant processes in lymph nodes is crucial.
  • This approach optimizes the application of resource-intensive ancillary diagnostic methods.