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Current and emerging treatments for vitiligo.

Michelle Rodrigues¹, Khaled Ezzedine², Iltefat Hamzavi³

¹Department of Dermatology, St. Vincent's Hospital, The Skin and Cancer Foundation Inc, Victoria, Australia; The Royal Children's Hospital, Victoria, Australia.

Journal of the American Academy of Dermatology

|June 17, 2017

Summary

Vitiligo is a treatable skin condition, not just cosmetic. Safe and effective therapies exist to halt progression, stabilize lesions, and promote repigmentation.

Keywords:

afamelanotide biologics corticosteroids excimer lamp excimer laser grafting leukoderma methotrexate narrowband ultraviolet light phototherapy pigmentation tacrolimus treatment vitiligo

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Area of Science:

Dermatology
Immunology

Background:

Vitiligo is often perceived as cosmetic, but it requires clinical management.
Recognizing diverse presentations and active disease is crucial for effective patient care.

Purpose of the Study:

To inform clinicians about vitiligo management beyond cosmetic concerns.
To review current and emerging treatments for vitiligo.

Main Methods:

Discussion of established treatments: topical and systemic immunosuppressants, phototherapy, and surgical techniques.
Analysis of strategies to optimize existing therapies.
Highlighting novel treatments for future efficacy.

Main Results:

Current treatments can halt vitiligo progression, stabilize depigmented areas, and stimulate repigmentation.
Optimization of existing therapies is key to managing vitiligo effectively.

Conclusions:

Vitiligo management requires awareness of its non-cosmetic nature and available treatments.
A combination of optimized current therapies and emerging treatments offers improved outcomes for vitiligo patients.