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Related Concept Videos

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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Related Experiment Video

Updated: Feb 28, 2026

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model
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Risk Factor Analysis of Recanalization Timing in Coiled Aneurysms: Early versus Late Recanalization.

J P Jeon1, Y D Cho2, D H Yoo3

  • 1From the Department of Neurosurgery (J.P.J.), Hallym University College of Medicine, Chuncheon, Korea.

AJNR. American Journal of Neuroradiology
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Coiled aneurysms ≤7 mm are more likely to achieve complete occlusion but prone to late recanalization, especially those 4-7 mm. Long-term imaging is recommended for aneurysms >4 mm to detect recanalization.

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Area of Science:

  • Neurosurgery
  • Interventional Radiology
  • Vascular Neurology

Background:

  • Long-term data on recanalization timing after aneurysm coiling is limited.
  • Understanding early vs. late recanalization is crucial for effective treatment.
  • Identifying risk factors for recanalization is essential for patient management.

Purpose of the Study:

  • To analyze and compare early and late recanalization rates after endovascular coiling.
  • To identify risk factors associated with early and late recanalization.
  • To evaluate the long-term outcomes of coiled aneurysms.

Main Methods:

  • Retrospective analysis of 870 coiled saccular aneurysms with a mean follow-up of 30.8 months.
  • Stratification into early recanalization (within 6 months), late recanalization (after 6 months), and complete occlusion groups.
  • Multinomial regression analysis to identify risk factors for recanalization.

Main Results:

  • Posterior circulation, subarachnoid hemorrhage, repeat coiling, and aneurysm size >7 mm were linked to early recanalization.
  • Aneurysms ≤7 mm were associated with late recanalization versus early recanalization.
  • Aneurysms 4-7 mm showed a predilection for late recanalization, while smaller lesions (≤7 mm) had increased complete occlusion rates.

Conclusions:

  • Aneurysms ≤7 mm are more prone to late recanalization, particularly those measuring 4-7 mm.
  • Despite higher rates of complete occlusion in smaller aneurysms, late recanalization necessitates vigilance.
  • Long-term follow-up imaging is recommended for aneurysms >4 mm to detect late recanalization.