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How RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes
1Cancer Research UK Nucleic Acid Structure Research Group, MSI/WTB Complex, The University of Dundee, Dow Street, Dundee DD1 5EH, U.K. d.m.j.lilley@dundee.ac.uk.
Biochemical Society Transactions
|June 17, 2017
Abstract:
Recent structural and mechanistic studies have shed considerable light on the catalytic mechanisms of nucleolytic ribozymes. The discovery of several new ribozymes in this class has now allowed comparisons to be made, and the beginnings of mechanistic groupings to emerge.
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