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Small intestinal peripheral nerve sheath tumour in a cat
Ariadna Ribas1, Rachel Miller1, Roberta Rasotto2
1Internal Medicine Service, Dick White Referrals, Station Farm, Six Mile Bottom, UK.
JFMS Open Reports
|June 17, 2017
Summary
This report details the first known case of a small intestinal peripheral nerve sheath tumor in a cat. Immunohistochemistry was crucial for diagnosis, adding a new differential for feline intestinal masses.
Area of Science:
- Veterinary Pathology
- Oncology
- Feline Medicine
Background:
- Peripheral nerve sheath tumors (PNSTs) are rare in domestic animals.
- Intestinal masses in cats can present with non-specific clinical signs like weight loss and inappetence.
- Accurate diagnosis of intestinal tumors is critical for appropriate treatment and prognosis.
Observation:
- A 5-year-old Chinchilla cat presented with a four-week history of weight loss and inappetence.
- Clinical investigation revealed a distal jejunal mass.
- Histopathological and immunohistochemical analyses were performed on the resected mass.
Findings:
- The jejunal mass was diagnosed as a peripheral nerve sheath tumor.
- Immunohistochemistry played a key role in differentiating this tumor from other mesenchymal neoplasms.
- This represents the first reported case of a small intestinal PNST in a feline patient.
Implications:
- This case expands the differential diagnosis list for intestinal masses in cats.
- Highlights the importance of advanced diagnostic techniques like immunohistochemistry in veterinary oncology.
- Contributes to the limited veterinary literature on feline gastrointestinal tumors.

