Meningocele manqué: a comprehensive review of this enigmatic finding in occult spinal dysraphism
Cameron Schmidt1, Ellie Bryant2, Joe Iwanaga2
1Seattle Science Foundation, 550 17th Ave., James Tower, Suite 600, Seattle, WA, 98122, USA. cameronkurtschmidt@gmail.com.
Abstract:
The term meningocele manqué (MM) was coined in 1972 to describe a broad range of surgical findings characterized by intradural bands tethering neural structures to the dorsal dura. Over the following decades, reports continued to lump intradural tethering bands associated with a variety of comorbidities under the umbrella term MM. In more recent years, disorders previously called MM have been identified as embryologically distinct and were reclassified. While this sectioning continues, there remains a set of intradural tethering disorders for which no better term than MM exists. Herein, we comprehensively review the literature surrounding MM, including embryological disorders, clinical, radiographic, and surgical presentation, as well as alternative classification methods and MM treatment.
Insights
Meningocele manqué (MM) describes intradural bands tethering neural structures. This review examines the evolving classification and treatment of these disorders, clarifying remaining cases.
Area of Science:
- Neurosurgery
- Developmental Biology
- Neuropathology
Background:
- Meningocele manqué (MM) was historically used for diverse intradural tethering findings.
- Recent reclassifications separate embryologically distinct disorders previously under the MM umbrella.
- A subset of intradural tethering disorders still lacks a definitive classification beyond MM.
Purpose of the Study:
- To comprehensively review the literature on meningocele manqué (MM).
- To discuss the embryological origins, clinical presentation, and diagnostic imaging of MM.
- To explore alternative classification systems and current treatment strategies for MM.
Main Methods:
- Systematic literature review of studies on meningocele manqué.
- Analysis of embryological development related to spinal cord tethering.
- Evaluation of clinical, radiographic, and surgical data from reported cases.
Main Results:
- The term MM has encompassed a heterogeneous group of intradural tethering disorders.
- Embryological distinctions have led to reclassification of some conditions previously termed MM.
- A core group of intradural tethering disorders remains under the MM classification pending further differentiation.
Conclusions:
- The historical term meningocele manqué (MM) requires careful consideration due to evolving classifications.
- Understanding the embryological basis is crucial for accurate diagnosis and management.
- Further research is needed to refine the classification and optimize treatment for persistent intradural tethering disorders.
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