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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Psoriasis & psoriatic therapies.

Wendy Cantrell1

  • 1Wendy Cantrell is an assistant professor and manager of clinical research at the University of Alabama at Birmingham Department of Dermatology, Birmingham, Ala.

The Nurse Practitioner
|June 17, 2017
PubMed
Summary

Psoriasis is a chronic inflammatory skin condition. This review covers its presentation, causes, and various treatment options, including topical agents, phototherapy, systemic therapies, and biologics.

Area of Science:

  • Dermatology
  • Immunology
  • Rheumatology

Background:

  • Psoriasis is a chronic, immune-mediated inflammatory disease.
  • It primarily affects the skin, causing characteristic lesions.
  • Psoriatic arthritis is a related condition affecting joints.

Purpose of the Study:

  • To provide a comprehensive overview of psoriasis.
  • To discuss the epidemiology, pathogenesis, and clinical presentation.
  • To review current and emerging treatment strategies.

Main Methods:

  • Literature review of psoriasis.
  • Synthesis of information on disease mechanisms.
  • Categorization of therapeutic approaches.

Main Results:

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  • Psoriasis exhibits diverse clinical presentations.
  • Pathogenesis involves complex immune system dysregulation.
  • A range of treatments exist, from topical to systemic and biologic therapies.

Conclusions:

  • Effective management of psoriasis requires understanding its multifaceted nature.
  • Treatment selection depends on disease severity and patient factors.
  • Ongoing research continues to refine therapeutic options for psoriasis and psoriatic arthritis.