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Updated: Feb 28, 2026
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
Published on: December 9, 2010
Nanoscale dose deposition in cell structures under X-ray irradiation treatment assisted with nanoparticles: An
W Melo-Bernal1, V Chernov2, G Chernov3
1Departamento de Investigación en Física, Doctorado en Física Universidad de Sonora, 83000 Hermosillo, Sonora, México.
Abstract:
In this study, an analytical model for the assessment of the modification of cell culture survival under ionizing radiation assisted with nanoparticles (NPs) is presented. The model starts from the radial dose deposition around a single NP, which is used to describe the dose deposition in a cell structure with embedded NPs and, in turn, to evaluate the number of lesions formed by ionizing radiation. The model is applied to the calculation of relative biological effectiveness values for cells exposed to 0.5mg/g of uniformly dispersed NPs with a radius of 10nm made of Fe, I, Gd, Hf, Pt and Au and irradiated with X-rays of energies 20keV higher than the element K-shell binding energy.
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