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Gamma-delta (γδ) T-cell lymphoma - another case unclassifiable by World Health Organization classification: a case
Hemant Sindhu1, Ruqin Chen1, Hui Chen1
1Division of Hematology/Oncology, Brookdale University Hospital Medical Center, Brooklyn, NY, 11212, USA.
Background:
We present a case of gamma-delta T-cell lymphoma that does not fit the current World Health Organization classifications.
Case Presentation:
A 74-year-old Caribbean-American woman presented with lymphocytosis, pruritus, and non-drenching night sweats. Bone marrow and peripheral blood analyses both confirmed the diagnosis of gamma-delta T-cell lymphoma. An axillary lymph node biopsy was negative for lymphoma. Clinically absent hepatosplenomegaly and skin lesions with biopsy-proven gamma-delta T-cell lymphoma suggest that she is unclassifiable within the current classification system.
Conclusions:
We believe this is a case of not otherwise specified gamma-delta T-cell lymphoma. Accumulation of these rare not otherwise specified cases will be important for future classification which further defines the biology of this disease.
