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Limbal xanthogranuloma in a dog.

Juri Ota-Kuroki1, Keiichi Kuroki2

  • 1Midwest Veterinary Referral Center-BluePearl, 17497 N. Outer 40 Drive, Chesterfield, Missouri, 63005, U.S.A.

The Journal of Veterinary Medical Science
|June 20, 2017
PubMed
Summary
This summary is machine-generated.

This study reports the first canine case of limbal xanthogranuloma, a rare eye condition. Surgical excision was necessary after medical treatments for the slow-growing temporal limbal mass failed.

Keywords:
doglimbusxanthogranuloma

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Area of Science:

  • Ophthalmology
  • Veterinary Medicine
  • Pathology

Background:

  • Canine nodular granulomatous episclerokeratitis is a common suspected diagnosis for limbal masses.
  • Ocular inflammatory conditions in dogs often require prompt and effective treatment.

Observation:

  • A 10-year-old female spayed American Pitt Bull Terrier presented with a slow-growing mass on the temporal limbus of the right eye.
  • Initial treatment with prednisolone acetate and tacrolimus ophthalmic solutions was unsuccessful.
  • The mass continued to grow, necessitating surgical intervention.

Findings:

  • Lamellar sclerokeratectomy was performed to excise the limbal mass.
  • Histopathological examination revealed granulomatous inflammation with intrahistiocytic lipids and cholesterol clefts.
  • The findings were consistent with canine limbal xanthogranuloma.

Implications:

  • This case represents the first documented instance of limbal xanthogranuloma in a canine patient.
  • Highlights the importance of considering xanthogranuloma in the differential diagnosis of canine limbal masses.
  • Suggests that surgical excision may be the definitive treatment for canine limbal xanthogranuloma when medical management fails.