Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Takayasu's disease in Arabs.

M A Sattar, A G White, B Eklof

    Postgraduate Medical Journal
    |May 1, 1985
    PubMed
    Summary

    This study reports four Arab women with Takayasu's arteritis, a rare inflammatory condition. Human leukocyte antigen (HLA) typing revealed shared antigens, suggesting a genetic predisposition in this ethnic group.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Complete genome sequence of dengue virus serotype 2 obtained from Chattogram, Bangladesh.

    Microbiology resource announcements·2025
    Same author

    Clinical spectrum and risk factors of severe dengue infection: findings from the 2023 dengue outbreak in Bangladesh.

    BMC infectious diseases·2025
    Same author

    Circulating dengue virus serotypes, demographics, and epidemiology in the 2023 dengue outbreak in Chittagong, Bangladesh.

    European journal of microbiology & immunology·2024
    Same author

    An Aspen plus process simulation model for exploring the feasibility and profitability of pyrolysis process for plastic waste management.

    Journal of environmental management·2024
    Same author

    Hydrodynamic performance assessment of photocatalytic reactor with baffles and roughness in the flow path: A modelling approach with experimental validation.

    Heliyon·2023
    Same author

    Non-Puerperal Chronic Inversion of Uterus Due to Big Fibroid Uterus in a Post-Menopausal Woman.

    Mymensingh medical journal : MMJ·2023

    Area of Science:

    • Immunogenetics
    • Rheumatology
    • Vascular Inflammation

    Background:

    • Takayasu's arteritis is a rare, chronic inflammatory disease affecting large arteries, primarily the aorta and its branches.
    • The etiology of Takayasu's arteritis remains largely unknown, with suspected autoimmune and genetic factors.
    • Previous research has explored associations between specific human leukocyte antigen (HLA) types and Takayasu's arteritis in various populations.

    Observation:

    • Four female Arab patients presented with classical clinical manifestations of Takayasu's arteritis.
    • Comprehensive human leukocyte antigen (HLA) phenotyping was performed on all affected individuals.
    • All four patients consistently exhibited the HLA antigens A2, A9, BW35, and DR7.

    Findings:

    • The consistent presence of specific HLA antigens (A2, A9, BW35, DR7) in all reported cases suggests a potential immunogenetic link.
    • This finding indicates a possible genetic susceptibility to Takayasu's arteritis within the Arab ethnic group.
    • The observed HLA associations provide novel insights into the pathogenesis of Takayasu's arteritis in this specific demographic.

    Implications:

    • These findings highlight the importance of considering ethnic-specific genetic factors in the immunopathogenesis of Takayasu's arteritis.
    • Further research into HLA associations in diverse populations is warranted to elucidate the genetic underpinnings of this condition.
    • Understanding these genetic predispositions may pave the way for improved diagnostic markers and targeted therapeutic strategies for Takayasu's arteritis.

    Related Experiment Videos