Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiomyopathy-Associated Mutations in a Hotspot Region at the C-Terminal Part of Desmin Coil-2 Domain Impair the Intermediate Filament Assembly.

Circulation. Genomic and precision medicine·2026
Same author

Spontaneous Imbibition of Bicontinuous Microemulsions into Hydrophilic and Hydrophobic Controlled Pore Glasses.

ACS omega·2026
Same author

The myofibrillar myopathy-linked variant DES-p.T341P impairs desmin filament assembly.

Molecular biology reports·2026
Same author

Atlas of Cardiomyopathy Associated <i>DES</i> (Desmin) Mutations: Functional Insights Into the Critical 1B Domain.

Circulation. Genomic and precision medicine·2025
Same author

Smart Copolymer Microgels with High Volume Phase Transition Temperatures: Composition, Swelling, and Morphology.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Heterogeneous Decoration of Ionic Mesopores by Ionic and Poly(Ionic) Liquids.

ACS applied materials & interfaces·2025

Related Experiment Video

Updated: Feb 28, 2026

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
12:22

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

8.8K

Core-Shell Microgel-Based Surface Coatings with Linear Thermoresponse.

Marian Cors1,2, Oliver Wrede1, Anne-Caroline Genix2

  • 1Department of Physical and Biophysical Chemistry, Bielefeld University , Universitaetsstrasse 25, 33615 Bielefeld, Germany.

Langmuir : the ACS Journal of Surfaces and Colloids
|June 20, 2017
PubMed
Summary
This summary is machine-generated.

Core-shell microgels show linear swelling behavior when adsorbed on silicon wafers. This response mirrors their behavior in suspension, offering insights into surface-adsorbed polymer networks.

More Related Videos

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

14.1K
Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.6K

Related Experiment Videos

Last Updated: Feb 28, 2026

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
12:22

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

8.8K
Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

14.1K
Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
09:09

Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

10.6K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Surface Science

Background:

  • Core-shell microgels are advanced polymer networks with tunable properties.
  • Understanding their behavior upon surface adsorption is crucial for applications in coatings, sensors, and drug delivery.
  • Poly(N-isopropylmethacrylamide) and poly(N-n-propylacrylamide) are known for their thermosensitive swelling characteristics.

Purpose of the Study:

  • To investigate the swelling and shrinking behavior of core-shell microgels adsorbed on silicon wafers.
  • To compare the adsorption behavior with the known suspension behavior of these microgels.

Main Methods:

  • Fabrication of core-shell microgels with a cross-linked poly(N-isopropylmethacrylamide) core and a poly(N-n-propylacrylamide) shell.
  • Adsorption of microgels onto silicon wafer substrates.
  • Characterization using ellipsometry and atomic force microscopy (AFM) to probe structural changes.

Main Results:

  • Core-shell microgels adsorbed on silicon wafers exhibit swelling and shrinking in response to temperature changes.
  • The observed swelling behavior in the adsorbed state is linear, consistent with their behavior in suspension.
  • The temperature interval between the lower critical solution temperatures of the core and shell polymers dictates the linear swelling response.

Conclusions:

  • Surface adsorption does not fundamentally alter the linear swelling response of these core-shell microgels.
  • The findings demonstrate the predictability of microgel behavior from solution to surface, important for material design.
  • Ellipsometry and AFM are effective tools for studying adsorbed microgel systems.