Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tardive dyskinesia: developmental factors.

R Yassa, A M Ghadirian, G Schwartz

    Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
    |August 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Seedling rescue from natural regeneration and use of Osmocote for production of Jacaranda copaia (Aubl.) D. Don seedlings.

    Brazilian journal of biology = Revista brasleira de biologia·2026
    Same author

    Overall survival from the open-label phase II trial of palbociclib in patients with advanced well-differentiated/dedifferentiated liposarcoma.

    ESMO open·2026
    Same author

    Osmocote accelerates seedling development and quality of the slow-growing species Vouacapoua americana Aubl.

    Brazilian journal of biology = Revista brasleira de biologia·2026
    Same author

    Author Correction: Tree diversity is changing across tropical Andean and Amazonian forests in response to global change.

    Nature ecology & evolution·2026
    Same author

    Tree diversity is changing across tropical Andean and Amazonian forests in response to global change.

    Nature ecology & evolution·2026
    Same author

    Seedling quality of Cordia trichotoma under different container volumes and fertilizers.

    Brazilian journal of biology = Revista brasleira de biologia·2025
    Same journal

    Treatment of Comorbid Alcohol Use Disorder and Major Depressive Disorder.

    Canadian journal of psychiatry. Revue canadienne de psychiatrie·2026
    Same journal

    Revisiting the Exercise Recommendations in the 2023 CANMAT Guidelines for Major Depressive Disorder.

    Canadian journal of psychiatry. Revue canadienne de psychiatrie·2026
    Same journal

    Prevalence of Comorbid Postpartum Depression and Anxiety in Birthing Parents Seeking Treatment for Postpartum Depression: Prévalence de la présence comorbide de la dépression et de l'anxiété post-partum chez les parents ayant accouché qui ont consulté en raison de la dépression post-partum.

    Canadian journal of psychiatry. Revue canadienne de psychiatrie·2026
    Same journal

    Healthcare Pattern of Use Before and After Initiating a Long-Acting Antipsychotic Among a Cohort of 6221 Patients With a History of Psychosis.

    Canadian journal of psychiatry. Revue canadienne de psychiatrie·2026
    Same journal

    Clinician's Corner: Chatbots for Psychotherapy.

    Canadian journal of psychiatry. Revue canadienne de psychiatrie·2026
    Same journal

    Understanding Illicit Prescription Painkiller Use: A Multivariable Exploration of Mental Health and Other Predictors Among Canadian University Students: Comprendre la consommation illicite d'analgésiques sur ordonnance : une analyse multivariée de la santé mentale et d'autres facteurs prédictifs chez les étudiants universitaires canadiens.

    Canadian journal of psychiatry. Revue canadienne de psychiatrie·2026
    See all related articles

    Long-term neuroleptic use can cause tardive dyskinesia (TD), an involuntary movement disorder. This study found that past drug-free periods were significantly more common in TD patients, suggesting a potential protective factor.

    Area of Science:

    • Neurology
    • Psychiatry

    Background:

    • Tardive dyskinesia (TD) is a movement disorder linked to long-term neuroleptic treatment.
    • Etiological factors for TD remain incompletely understood, with conflicting research findings.
    • Identifying specific risk or protective factors is crucial for understanding TD development.

    Purpose of the Study:

    • To compare etiological factors between patients with tardive dyskinesia (TD) and a control group.
    • To investigate the role of medication history, including drug-free periods, in TD.
    • To identify statistically significant differences that may explain TD development.

    Main Methods:

    • A case-control study comparing 17 patients with TD to 17 non-TD controls.
    • Analysis of factors including total neuroleptic and antiparkinsonian medication intake.

    Related Experiment Videos

  • Evaluation of past drug-free periods in patient histories.

    • Main Results:

    • No significant differences were found in total neuroleptic or antiparkinsonian medication intake between groups.
    • No significant differences were observed regarding organicity between TD patients and controls.
    • Statistically significant differences (P < 0.025) were found in the duration of past drug-free periods, being longer in TD patients.

    Conclusions:

    • Past drug-free periods appear to be a significant factor differentiating TD patients from controls.
    • This finding suggests that periods without neuroleptic exposure may play a role in the development or prevention of TD.
    • Further research is warranted to elucidate the mechanisms behind this association.