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Mark E Josephson: A Tribute to His Work on Ventricular Arrhythmias
1University of Pennsylvania Health System, Philadelphia, USA.
Arrhythmia & Electrophysiology Review
|June 21, 2017
Summary
Dr. Josephson pioneered evaluating and managing ventricular arrhythmias. His bold methods in the 1970s involved programmed stimulation to test antiarrhythmic drugs, pushing invasive cardiac arrhythmia management boundaries.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Arrhythmias
Background:
- Dr. Josephson's pioneering work focused on ventricular arrhythmias.
- His approach to evaluation and management was considered bold for its time.
Purpose of the Study:
- To highlight Dr. Josephson's innovative contributions to cardiac arrhythmia management.
- To underscore the early development of invasive diagnostic techniques.
Main Methods:
- Utilized programmed right ventricular stimulation.
- Assessed antiarrhythmic drug efficacy through invasive testing.
Main Results:
- The methods pushed the risk limits of invasive cardiac arrhythmia management.
- Established early benchmarks for antiarrhythmic drug testing.
Conclusions:
- Dr. Josephson's research laid groundwork for modern arrhythmia treatment.
- Pioneering techniques in the 1970s advanced the field of cardiac electrophysiology.
