Related Experiment Video
Updated: Feb 28, 2026

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Metal-Free Oxidative C-C Bond Functionalization of Methylenecyclopropanes with Ethers Leading to 2-Substituted
Yu Liu1, Qiao-Lin Wang1, Cong-Shan Zhou1
1Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology , Yueyang 414006, China.
Abstract:
A novel metal-free oxidative ring-opening/cyclization of methylenecyclopropanes with ethers was established for the synthesis of diverse 2-substituted 3,4-dihydronaphthalenes with high selectivity and efficiency. This oxidative cyclization is achieved by C(sp3)-H functionalization, ring-opening, and cyclization, and this method represents a new example of methylenecyclopropane oxidative cyclization with an aromatic carbon and a C(sp3)-H bond by simultaneously forming two new carbon-carbon bonds.
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