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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
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Microbiota, Inflammation and Colorectal Cancer

Cécily Lucas1, Nicolas Barnich2, Hang Thi Thu Nguyen3

  • 1M2iSH, UMR 1071 Inserm, University of Clermont Auvergne, INRA USC 2018, Clermont-Ferrand 63001, France. cecily.lucas@uca.fr.

International Journal of Molecular Sciences
|June 21, 2017
PubMed
Summary

The gut microbiome influences colorectal cancer (CRC) development. This review explores how specific bacteria promote CRC through inflammation, genotoxins, and toxic metabolites, and discusses microbiota-targeted therapies.

Keywords:
colorectal cancergenotoxinshost-pathogen interactioninflammationintestinal microbiota

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