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Callosal Motor Impersistence: A Novel Disconnection Syndrome
Hee Jin Kim1, Dongyeop Kim, Da-Heen Won
1*Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea †Neuroscience Center, Samsung Medical Center, Seoul, Republic of Korea ‡Department of Clinical Research Design and Evaluation ¶Department of Health Sciences and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea §Department of Neurology, University of Florida, Gainesville, Florida ∥Veterans Affairs Medical Center, Gainesville, Florida.
Motor impersistence, the inability to sustain movement, can occur after right hemisphere damage. This case shows isolated callosal injury can cause temporary motor impersistence in dominant limbs.
Area of Science:
- Neuroscience
- Neurology
Background:
- Motor impersistence is a motor-intentional disorder often linked to right hemisphere lesions.
- The right hemisphere typically mediates motor persistence, with callosal lesions potentially causing impersistence in contralateral limbs.
Observation:
- A 65-year-old man experienced transient left leg movement loss after an undiagnosed left callosal infarction.
- He presented with signs of callosal disconnection, including left-hand agraphia, apraxia, and tactile anomia.
- Despite no limb weakness, he exhibited motor impersistence, unable to sustain right arm and leg extension.
Findings:
- The patient demonstrated temporary motor impersistence in his dominant limbs (right arm and leg).
- Symptoms resolved within three months post-infarction.
- This suggests motor impersistence can arise from isolated callosal injury disrupting interhemispheric communication.
Implications:
- Isolated callosal injuries can lead to motor impersistence in dominant limbs.
- Highlights the role of interhemispheric connections in maintaining motor control.
- Underscores the importance of considering callosal disconnection in motor-intentional disorders.
