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Noninvasive Nuclear SPECT Myocardial Blood Flow Quantitation to Guide Management for Coronary Artery Disease
Lung-Ching Chen1, Bor-Hsin Jong, Sheng-Che Lin
1From the *Division of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei; †School of Medicine, Fu Jen Catholic University, New Taipei City; ‡Department of Nuclear Medicine, Shin Kong Wu Ho Su Memorial Hospital, Taipei; §Department of Medical Physics Research, Bailing Cloud Biomedical Technologies Innovation, Taipei, Taiwan; and ∥Nuclear Science and Engineering Institute, University of Missouri-Columbia, Columbia, MO.
Abstract:
Recently, myocardial blood flow quantitation with dynamic SPECT has been validated to enhance the detection of multivessel coronary artery disease (CAD) and conclude equivocal SPECT myocardial perfusion study. This advance opened an important clinical application to utilize the tool in guiding CAD management for area where myocardial perfusion tracers for PET are unavailable or unaffordable. We present a clinical patient with ongoing recursive angina who underwent multiple nuclear stress tests for a sequence of CAD evaluation in 26 months and demonstrated that SPECT myocardial blood flow quantitation properly guided CAD management to warrant patient outcome.
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