Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

385
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
385
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

977
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
977
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

2.8K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
2.8K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

575
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
575

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Comprehensive Analysis of Diagnostic and Virological Surveillance During the 2023-2025 Measles Epidemic Scenario.

Diagnostics (Basel, Switzerland)·2026
Same author

Chikungunya resurgence in Italy: a signal of vectorborne viruses changing pattern in the era of climate change?

Frontiers in public health·2026
Same author

A case of Human Pegivirus acute febrile infection diagnosed by Next Generation Sequencing (NGS).

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026
Same author

Intervention studies and antimicrobial resistance in Italy: An overview of the latest evidence.

Journal of global antimicrobial resistance·2026
Same author

West Nile virus spread in Italy, summer 2025: a climate change hallmark?

Frontiers in public health·2025
Same author

Molecular investigation on measles cases rise and variants co-circulation in the Lazio region, Italy.

Virology journal·2025

Related Experiment Video

Updated: Feb 28, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
06:04

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

2.9K

Mumps clinical diagnostic uncertainty.

Fabio Magurano1, Melissa Baggieri1, Antonella Marchi1

  • 1National Reference Laboratory for Measles and Rubella, Department of Infectious Diseases, National Institute of Health, Rome, Italy.

European Journal of Public Health
|June 22, 2017
PubMed
Summary

Mumps outbreaks occur even in vaccinated populations. Laboratory diagnosis is crucial to differentiate mumps from Epstein-Barr virus (EBV) infections, which present similar symptoms and were found in nearly 20% of suspected cases.

More Related Videos

Identification of Mycobacterium Species by DNA Microarray Chip Method
06:27

Identification of Mycobacterium Species by DNA Microarray Chip Method

Published on: June 24, 2025

671
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

2.1K

Related Experiment Videos

Last Updated: Feb 28, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
06:04

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

2.9K
Identification of Mycobacterium Species by DNA Microarray Chip Method
06:27

Identification of Mycobacterium Species by DNA Microarray Chip Method

Published on: June 24, 2025

671
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

2.1K

Area of Science:

  • Infectious Diseases
  • Vaccinology
  • Virology

Background:

  • Mumps outbreaks persist globally despite widespread measles, mumps, and rubella (MMR) vaccination.
  • Clinical diagnosis of mumps can be challenging due to similar symptoms caused by other viruses, including Epstein-Barr virus (EBV).
  • Accurate laboratory diagnosis is essential for differentiating mumps from other conditions presenting with parotid gland swelling.

Purpose of the Study:

  • To evaluate the accuracy of clinical mumps diagnosis in Italy.
  • To investigate the prevalence of Epstein-Barr virus (EBV) in suspected mumps cases with negative mumps virus results.
  • To establish differential diagnosis protocols for mumps-like illnesses.

Main Methods:

  • Retrospective analysis of 131 suspected mumps cases from 2007-2016 in Italy.
  • Differential diagnosis focusing on EBV in cases negative for mumps virus (molecular/serological tests).
  • Identification of EBV type in positive cases.

Main Results:

  • Epstein-Barr virus (EBV) was identified as the causative agent in 19.8% of suspected mumps cases.
  • All EBV-positive cases were attributed to EBV type 1.
  • This highlights a significant rate of EBV misdiagnosis for mumps.

Conclusions:

  • Laboratory-based differential diagnosis is critical for accurate identification of infectious diseases with mumps-like symptoms.
  • Distinguishing between mumps and EBV-related mononucleosis is particularly important.
  • This study underscores the need for robust diagnostic methods beyond clinical presentation.