Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Genetically proxied inhibition of cholesterol-lowering drug targets and survival in HPV-positive and non-HPV driven head and neck cancer: a multicentre MR study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2026

Same author

Selective muscle involvement quantification in late-onset Tay Sachs and Sandhoff disease using neuromuscular ultrasound imaging.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026

Same author

Botulinum toxin use in patients with neurological disorders: A U.S.-based claims database analysis.

PM & R : the journal of injury, function, and rehabilitation·2026

Same author

DaxibotulinumtoxinA for Injection in Adults with Cervical Dystonia: Clinical Insights from a Real-World Early Experience Program.

Movement disorders clinical practice·2026

Same author

Editorial: TOXINS 2026: 8th International Conference.

Toxicon : official journal of the International Society on Toxinology·2025

Same author

Sonomyography accurately captures joint kinematics during volitional and electrically stimulated motion in healthy adults and an individual with cerebral palsy.

Journal of neuroengineering and rehabilitation·2025

Search research articles

Related Experiment Video

Updated: Feb 28, 2026

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

Spasticity Video Challenge: A Look at Methods for Addressing Difficult Cases.

Katharine E Alter¹, Mark Gormley², Atul T Patel³

¹Mount Washington Pediatric Hospital, AT Still University, Mesa, Arizona, United States.

PM & R : the Journal of Injury, Function, and Rehabilitation

|June 22, 2017

Summary

This summary is machine-generated.

Spasticity management requires a comprehensive approach, combining various therapies to address unique patient needs. Botulinum toxin is valuable but should complement, not replace, other treatments for upper motor neuron syndromes.

More Related Videos

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

Corticospinal Excitability Modulation During Action Observation

Corticospinal Excitability Modulation During Action Observation

Published on: December 31, 2013

Related Experiment Videos

Last Updated: Feb 28, 2026

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

Corticospinal Excitability Modulation During Action Observation

Corticospinal Excitability Modulation During Action Observation

Published on: December 31, 2013

Area of Science:

Neurology
Physical Medicine and Rehabilitation

Background:

Spasticity, a common symptom of upper motor neuron syndromes (traumatic brain injury, stroke, cerebral palsy), significantly impacts patient function.
Current treatment paradigms involve a combination of interventions.

Purpose of the Study:

To outline a multifaceted treatment strategy for spasticity.
To emphasize individualized patient assessment and goal setting.

Main Methods:

Review of current therapeutic options for spasticity.
Emphasis on personalized assessment of impairments and functional impact.

Main Results:

Treatment of spasticity is complex and requires a combination of chemodenervation, systemic medications, surgery, and rehabilitation.
Individualized assessment is crucial for effective management.

Conclusions:

Botulinum toxin is a key component for symptomatic relief and functional improvement in hypertonia.
Botulinum toxin should rarely be the sole treatment modality for spasticity.