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Does atopy affect the course of viral pneumonia?

S B Erdem1, D Can1, S Girit2

  • 1Dr Behcet Uz Children's Hospital, Department of Pediatric Allergy, Izmir, Turkey.

Allergologia Et Immunopathologia
|June 22, 2017
PubMed

Insights

Atopy itself did not predict severe viral pneumonia in children. However, parental asthma, a history of wheezing, and exposure to environmental tobacco smoke were identified as significant risk factors for severe disease.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology
  • Infectious Diseases

Background:

  • Atopy is a known risk factor for severe respiratory symptoms in children.
  • Viral pneumonia is a common cause of hospitalization in pediatric patients.

Purpose of the Study:

  • To investigate the impact of atopy on the clinical course of viral pneumonia in hospitalized children.
  • To identify risk factors associated with severe viral pneumonia in pediatric patients.

Main Methods:

  • A multicenter study included 280 children aged 1-6 years hospitalized with viral pneumonia (2013-2016).
  • Patients were categorized into mild-moderate and severe pneumonia groups.
  • Atopy was assessed via skin prick tests, and risk factors for severe disease were analyzed.

Main Results:

  • Severe pneumonia occurred in 30.4% of patients.
  • Atopic sensitization was present in 21.4% of children.
  • Risk factors for severe viral pneumonia included parental asthma (RR: 1.5), ever wheezing (RR: 1.6), and environmental tobacco smoke exposure (RR: 1.6).

Conclusions:

  • The frequency of atopy did not differ between mild-moderate and severe pneumonia groups.
  • Parental asthma, prior wheezing, and environmental tobacco smoke are significant risk factors for severe viral pneumonia in children.
Abstract

Keywords:
AtopyChildrenViral pneumonia

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