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Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices

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Angioedema: Perioperative management.

Andrew A Maynard¹, Christina F Burger², Joseph J Schlesinger¹

¹Department of Anesthesiology and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

SAGE Open Medical Case Reports

|June 22, 2017

Summary

This summary is machine-generated.

Perioperative management of acquired angioedema (AAE) requires a tailored plan. This case highlights successful surgical outcomes with proactive prophylaxis and standby treatments for AAE patients.

Keywords:

C1-inhibitor Perioperative acquired angioedema airway anesthesiology angioedema hereditary angioedema laryngeal edema mast cell

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Area of Science:

Anesthesiology
Allergy and Immunology
Gastroenterology

Background:

Acquired angioedema (AAE) presents complex perioperative challenges, particularly in patients with gastrointestinal stromal tumors.
This case involves a 66-year-old male with AAE, urticaria, and mastocytosis admitted for urgent gastric surgery.

Observation:

The patient experienced severe AAE attacks with rash, abdominal pain, and respiratory distress.
Preoperative management included fresh frozen plasma and home prednisone, with C1-inhibitor and epinephrine on standby.

Findings:

The patient underwent urgent laparoscopic partial gastrectomy without intraoperative complications.
Discharge occurred three days post-procedure, indicating successful perioperative management.

Implications:

Developing patient-specific perioperative plans is crucial for optimizing outcomes in AAE patients undergoing surgery.
Prophylaxis, rescue therapies, and opioid-sparing strategies are essential components of AAE management during urgent surgical procedures.