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Published on: July 16, 2018
A Nanosensor Based on Carbon Dots for Recovered Fluorescence Detection Clenbuterol in Pork Samples
Yalan Liu1, Qiujun Lu1, Xiaojun Hu1
1Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, 410081, People's Republic of China.
Abstract:
Clenbuterol (CLB), a member of β-agonist family, has now been a serious threat to human health due to its illegal usage in the animal feed. In this paper, we designed a fluorescence resonance energy transfer (FRET) system consisting of carbon dots (C-dots) and gold nanoparticles (AuNPs) for recovered fluorescence detecting of CLB. In the presence of CLB, CLB molecules can interact with AuNPs via Au-N bonds, preventing the interaction of C-dots and AuNPs, which induced the recover of the fluorescent intensity. Under the optimal conditions, the limit of detection for CLB was 3 nM, with a wide concentration linear range of 8-200 nM (S/N = 3). Meanwhile, the proposed method was successfully applied to detect CLB in pork samples, illustrating it could be used as a reliable, rapid, and cost-effective method for the determination of CLB residues in pork samples.
