Related Experiment Video
Updated: Feb 28, 2026
07:54
Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
20.8K
Sleep-disordered breathing: clinical features, pathophysiology and diagnosis
Sebastian Robert Ott1, Lyudmila Korostovtseva2, Markus Schmidt3
1Department of Pulmonary Medicine, University Hospital (Inselspital) and University Bern, Switzerland; Interdisciplinary Sleep Wake Centre (SWEZ), University Hospital (Inselspital) and University Bern, Switzerland.
Swiss Medical Weekly
|June 22, 2017
Summary
Sleep-disordered breathing (SDB) is increasingly common and linked to cardiovascular and cerebrovascular diseases. Early screening for at-risk populations is recommended, though treatment benefits remain debated.
Area of Science:
- Cardiology
- Neurology
- Sleep Medicine
- Epidemiology
Background:
- Sleep-disordered breathing (SDB) prevalence is rising due to obesity and aging.
- SDB is associated with significant cardiovascular and cerebrovascular diseases, including hypertension, coronary heart disease, and stroke.
- Growing evidence links SDB to adverse long-term cardiovascular morbidity and mortality.
Purpose of the Study:
- To summarize epidemiological data on SDB and its link to cardio- and cerebrovascular disorders.
- To explore the pathophysiological mechanisms connecting SDB with cardiovascular and cerebrovascular diseases.
- To provide a critical overview of current SDB diagnostic procedures.
Main Methods:
- Review of epidemiological studies investigating SDB and cardiovascular/cerebrovascular outcomes.
- Analysis of pathophysiological pathways implicated in SDB-related diseases.
- Critical evaluation of diagnostic tools and screening strategies for SDB.
Main Results:
- SDB is a significant risk factor for hypertension, coronary heart disease, and stroke.
- Systematic screening for SDB is advised in high-risk populations due to potential long-term health effects.
- The long-term benefits of SDB treatment and optimal management strategies require further investigation.
Conclusions:
- SDB poses a considerable threat to cardiovascular and cerebrovascular health.
- Further research is needed to clarify the prognostic impact of SDB treatments.
- A comprehensive understanding of SDB's pathophysiology and diagnostics is crucial for effective management.
More Related Videos
Related Concept Videos
01:21Sleep Apnea
641
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
641
01:17Other Pulmonary Disorders
1.8K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.8K
01:20COPD: Pathogenesis and Clinical Features
2.0K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
2.0K
01:30Alterations in Respiration II
2.0K
There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
2.0K
01:15REM Sleep Behavior Disorder
2.1K
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
2.1K
01:24Sleep-Wake Cycles
3.1K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
3.1K