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Updated: Feb 28, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
[It is all about the form - adrenaline in anaphylaxis: intravenous or intramuscular administration?]
M van der Have1, D Dekker, E M J Theunissen
1Meander Medisch Centrum, afd. Maag-, Darm- en Leverziekten, Amersfoort.
Background:
Medication errors are a frequent problem in the accident and emergency (A&E) department.
Case Description:
A 17-year-old boy was referred to our A&E department with an anaphylactic reaction to peanuts. Because of various shortcomings in the care process in A&E, adrenaline was administered intravenously instead of intramuscularly, resulting in a broad complex tachycardia. We analysed these shortcomings using the 'Prevention and recovery information system for monitoring and analysis' (PRISMA) method.
Conclusion:
Medication errors are usually a result of shortcomings in non-technical skills, such as communication and situational awareness. Training these skills by applying the concept 'Crew resource management' may reduce medication errors and improve patient safety.
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