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Updated: Feb 28, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
[Poststroke depression - a common medical and social problem]
M Yu Maximova1, T Yu Chochlova2, E T Suanova2
1Research Center of Neurology, Moscow; Evdokimov Moscow State Medical Dentistry University, Moscow.
Abstract:
Poststroke depression (PD) is considered as a common medical and social problem. Depression is estimated to occur in 30-35% of the patients during the first year after stroke. Despite the high level of comorbidity, PD is frequently undetectedand and untreated. Psychological impairment from stroke has a negative effect on functional outcome, rehabilitation and quality of live. On the basis of literature review present prevalence, etiology, pathogenesis,diagnosis of PD and summarize current recommendations for therapeutic intervention. A rational approach to the treatment and prevention of PD is proposed.
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